P2O5/Al2O3: An efficient and Reusable Catalyst for the Synthesis of Trisubstituted Imidazoles under solvent- free conditions

Mona Esmaeilzadeh; Sadegh Allameh; Hossein Behmadi

2016 Volume 3 Issue 4

P2O5/Al2O3: An efficient and Reusable Catalyst for the Synthesis of Trisubstituted Imidazoles under solvent- free conditions

Mona Esmaeilzadeh, Sadegh Allameh, Hossein Behmadi

Abstract

An efficient and simple one-pot multicomponent procedure for the synthesis of imidazoles from the condensation of benzyl, ammonium acetate and aromatic aldehydes in the presence of a catalytic amount of alumina-supported phosphorus pentoxide /Al2O3 (P2O5/Al2O3) under solvent- free conditions is reported.

Keywords: Imidazoles, P2O5/Al2O3, Solvent- free conditions, Reusable catalyst;

PDF

References

M. H. Alizadeh, H. Razavi, F.F. Bamoharram. J. Mol. Cat., 2003; 206, 89.

J. Zhu, H. Bienayme, H. Multicomponent Reactions. Wiley-VCH: Weinheim, 2005.

V. P. Litvinov, Russ. Chem. Rev., 2003; 72, 69.

I. Ugi, A. Domling, W. Horl. Endeavour. 1994; 18, 115.

L. F. Tietze, A. Modi, Med. Res. Rev., 2000; 20, 304.

I. Ugi, A. Dömling, B. Werner, J. Heterocycl. Chem. 2000; 37, 647.

S. A. Laufer, W. Zimmermann, K. J. Ruff, J. Med. Chem., 2004; 47, 6311.

S. E. Wolkenberg, D. D. Wisnoski, W. H. Leister, Y. Wang, Org. Lett., 2004; 6, 1453.

J. G. Lombardino, E. H. Wiseman, J. Med. Chem., 1974; 17, 1182.

S. Samai, G. C. Nandi, P. Singh, M.S. Singh, Tetrahedron. 2009; 65.

G. V. M. Sharma, Y. Jyothi, P. S. Lakshmi, Synth. Commun. 2006; 36.

S. D. Sharma, P. Hazarika, D. Konwar, Tetrahedron Lett. 2008; 49.

S. Kantevari, S. V. N. Vuppalapati, D. O. Biradar, L. Nagarapu, J. Mol. Catal. 2007; 266.

B. Sadeghi, B.B.F. Mirjalili, M.M. Hashemi, Tetrahedron Lett, 2008; 49.

M. M. Heravi, F. Derikvand, F. F. Bamoharram, J. Mol. Catal., 2007; 263.

L. M. Wang, Y. H. Wang, H. Tian, J. Fluor. Chem., 2006; 127.

A. Hasaninejad, A. Zare, M. Shekouhy, J. Ameiri Rad, J. Comb. Chem, 2010; 12.

M. M. Heravi, K. Bakhtiari, H. A. Oskooie, S. Taheri, J. Mol. Catal., 2007; 263.

S. Allameh, M. M. Heravi, M. M. Hashemi, F. Bamoharram, Chines Chemical Letters. 2011; 22, 131.

A. Davoodnia, S. Allameh, S. Fazli, N. Tavakoli- Hoseini, Chemical papers., 2011; 65, 5.

G. Yasaghi, A. Davoodnia, S. Allameh, A. Zare- Bidaki, N. Tavakoli- Hoseini, Bull. Korean Chem Soc., 2012; 33, 8.

M. Roshani, S. Allameh, E. Darkooti, Asian Journal of Chemistry, 2013; 125, 4.

M. Ashrafi, A. Davoodnia, N. Tavakoli- Hoseini, Bull. Korean Chem Soc., 2013; 34, 5.

Entomology and Applied Science Letters is an international double-blind peer reviewed publication which publishes scientific research & review articles related to insects that contain information of interest to a wider audience, e.g. papers bearing on the theoretical, genetic, agricultural, medical and biodiversity issues. Emphasis is also placed on the selection of comprehensive, revisionary or integrated systematics studies of broader biological or zoogeographical relevance. In addition to full-length research articles and reviews, the journal publishes interpretive articles in a Forum section, Short Communications, and Letters to the Editor. The journal publishes reports on all phases of medical entomology and medical acarology, including the systematics and biology of insects, acarines, and other arthropods of public health and veterinary significance.

Announcement and Advertisement
Announcements regarding scientific activities such as conferences, symposium, are published for free. Advertisements can be either published or placed on website as banners.

Publisher
Institute of Pharmaceutical Sciences (IPS) , University of Veterinary and Animal Sciences, Lahore Pakistan.

Associations

Entomology and Applied Science Letters supports the submission of entomological papers that contain information of interest to a wider reader groups e. g. papers bearing on taxonomy, phylogeny, biodiversity, ecology, systematic, agriculture, morphology. The selection of comprehensive, revisionary or integrated systematics studies of broader biological or zoogeographical relevance is also important. Distinguished entomologists drawn from different parts of the world serve as honorary members of the Editorial Board. The journal encompasses all the varied aspects of entomological research.