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Creative Commons License 2019 Volume 6 Issue 2

Hepatoprotective Effects of Capparis spinosa L. Fruit Extract in Mice‎ ‎

Sareh Jahanbakhsh, Mehrdad Khatami, Massumeh Niazi, Alireza Moayyedkazemi
Abstract

Objective: The aim of this study is to evaluate the hepatoprotective effect of methanolic and aqueous extract of Capparis spinosa L. fruit in mice. Methods: The hepatoprotective effects of methanolic extract of C. spinosa was assessed by measuring the serum levels of enzymes including bilirubin, alkaline phosphatase (ALP), aspartate aminotransferase (AST), and alanine aminotransferase (ALT) in the treated mice after oral administration of C. spinosa at the doses of 250, 500, and 750 µg/kg, respectively, for 14 days. Results: The results demonstrated that C. spinosa at the tested doses of 250, 500, and 750 mg/kg had no significant toxicity on the serum liver enzymes of ALT, AST, ALP, and bilirubin. Conclusion: The findings revealed the hepatoprotective effects of methanolic extract of C. spinosa in mice‎.

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Entomology and Applied Science Letters is an international double-blind peer reviewed publication which publishes scientific research & review articles related to insects that contain information of interest to a wider audience, e.g. papers bearing on the theoretical, genetic, agricultural, medical and biodiversity issues. Emphasis is also placed on the selection of comprehensive, revisionary or integrated systematics studies of broader biological or zoogeographical relevance. In addition to full-length research articles and reviews, the journal publishes interpretive articles in a Forum section, Short Communications, and Letters to the Editor. The journal publishes reports on all phases of medical entomology and medical acarology, including the systematics and biology of insects, acarines, and other arthropods of public health and veterinary significance.

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Entomology and Applied Science Letters supports the submission of entomological papers that contain information of interest to a wider reader groups e. g. papers bearing on taxonomy, phylogeny, biodiversity, ecology, systematic, agriculture, morphology. The selection of comprehensive, revisionary or integrated systematics studies of broader biological or zoogeographical relevance is also important. Distinguished entomologists drawn from different parts of the world serve as honorary members of the Editorial Board. The journal encompasses all the varied aspects of entomological research.