2018 Volume 5 Issue 1

Study of Intra-Abdominal Adhesion After Hernia Repair with Propylene Mesh in Comparison with Amniotic Membrane Attached with Propylene Mesh in an Animal Model


Saba Ebrahimian, Sedigheh Tahmasbi, Ali Mohammad Bananzade, Farid Nasr Esfahani, Sedigheh Nadri, Abolfazl Abbaszadeh
Abstract

Adhesions after surgery are a common cause of surgical morbidity and can lead to mechanical small bowel obstruction, female infertility and chronic pelvic pain. The aim of this study is to compare the adhesion formation after repair of hernia with propylene mesh alone and propylene mesh attached to human amniotic membrane in rats to evaluate the effect of human amniotic membrane in reducing postoperative intra-abdominal adhesion. Twenty female non-pregnant healthy rats were randomized in the case (10) and control (10) groups, and full-thickness abdominal wall defect was created in each animal. In the case group, the defect was repaired with human amniotic membrane attached to propylene mesh, and in the control group with propylene mesh alone. The rats were re-operated one month later for investigation and measurement of the intra-abdominal adhesion band formation. Adhesion development was quantitated according to Nair's classification system (NCS). The data were also analyzed with Mann-Whitney U test. In the case group, 2 rats had grade 2 adhesions, and 8 had grade 3. In the control group, 3 had grade 2 adhesions and 7 had grade 3 adhesion bands. Besides, we had 3 infected wounds in the amniotic membrane group. Although amniotic membrane has shown good effect in some previous studies, in our investigation it was not effective. In addition, it increased the rate of infection in the case group, so more studies are recommended to have exact knowledge about effectiveness of amniotic membrane in reducing postoperative intra-abdominal adhesion


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References

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Entomology and Applied Science Letters is an international peer reviewed publication which publishes scientific research & review articles related to insects that contain information of interest to a wider audience, e.g. papers bearing on the theoretical, genetic, agricultural, medical and biodiversity issues. Emphasis is also placed on the selection of comprehensive, revisionary or integrated systematics studies of broader biological or zoogeographical relevance. Papers on non-insect groups are no longer accepted. In addition to full-length research articles and reviews, the journal publishes interpretive articles in a Forum section, Short Communications, and Letters to the Editor. The journal publishes reports on all phases of medical entomology and medical acarology, including the systematics and biology of insects, acarines, and other arthropods of public health and veterinary significance.
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Entomology and Applied Science Letters supports the submission of entomological papers that contain information of interest to a wider reader groups e. g. papers bearing on taxonomy, phylogeny, biodiversity, ecology, systematic, agriculture, morphology. The selection of comprehensive, revisionary or integrated systematics studies of broader biological or zoogeographical relevance is also important. Distinguished entomologists drawn from different parts of the world serve as honorary members of the Editorial Board. The journal encompasses all the varied aspects of entomological research. This has become the need felt in scientific research due to the emphasis on intra-, inter-, and multi-disciplinary approach.