2018 Volume 5 Issue 1

Evaluation of the Sub-Acute Toxicity Effects of Amygdalus Eburnea Spach Extract in Mice


Mahdi Rezaeifar, Maryam Rezaeifar
Abstract

To date, the use of medicinal herbs for therapeutic purposes is very common; however, it is required to find the scientific validations for their side effects. This study aimed at identifying the toxicity effects of Amygdalus eburnea Spach extract on hematological and biochemical parameters in mice. Toxicity effects of N. tripedale extract were assessed by evaluating the biochemical and hematological parameters of the treated mice after oral administration of A. eburnea extract at the doses of 250, 500, and 750 mg/kg for 14 days. The results demonstrated that A. eburnea extract at the tested doses did not have considerable toxicity on the biochemical parameters of ALT, AST, ALP, and bilirubin used for the assessment of the liver function, and also Cr and BUN for renal function as well as hematological parameters such as HGB, Hct, WBC, RBC, and PLT counts. But further investigations are compulsory to determine other toxicity features such as genotoxicity, and chronic toxicity.


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Entomology and Applied Science Letters is an international peer reviewed publication which publishes scientific research & review articles related to insects that contain information of interest to a wider audience, e.g. papers bearing on the theoretical, genetic, agricultural, medical and biodiversity issues. Emphasis is also placed on the selection of comprehensive, revisionary or integrated systematics studies of broader biological or zoogeographical relevance. Papers on non-insect groups are no longer accepted. In addition to full-length research articles and reviews, the journal publishes interpretive articles in a Forum section, Short Communications, and Letters to the Editor. The journal publishes reports on all phases of medical entomology and medical acarology, including the systematics and biology of insects, acarines, and other arthropods of public health and veterinary significance.
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